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“What is fibroblast” They are our cells responsible for the production of tissue and collagen between cells that is usually called “connective tissue” in our body. Together, the intercellular tissue (extracellular matrix) and collagen provide tissue formation from cells. The continuity of these structures with the sustainability and the elastic properties of the tissues and playing a part in repairing the damages of these tissues. Therefore, fibroblasts are one of the most important connective tissue elements of our body.
Fibroblasts are active cells. There are many substances they synthesize and secrete,
glycosaminoglycans, collagen substances, elastic substances, reticular (reticular) building blocks and
glycoprotein substances are some of the substances they synthesize.
Fibrocytes are the inactive cell types of fibroblasts found in tissue. When a tissue damage occurs, fibrocytes are stimulated and multiplied by transforming into fibroblasts. We can say that our fibroblasts are “the skillful and hardworking restoration architects” of our body. They play a key role
in the repair of tissue damage with the substances they secrete.
So, "Can fibroblasts reproduce outside the body?" The answer to the question is “Yes, it can be reproduced” which is pleasing to all of us.
Because fibroblasts can be easily removed by biopsy. They can be reproduced in the laboratory and in a controlled production process called cell culture. Since these cells are not fully differentiated from each other but have high potential, they can multiply rapidly in cell culture stage and can be stored by freezing. From time to time, they can be used by thawing them from frozen state. This process of producing cells is called cell passage. Passage can be done a certain number of times. Fibroblast cells are also a very good source for experimental studies, thanks to their ability to be refrozen and stored.
Why have fibroblast cells become more important ?
Fibroblasts, which are responsible for wound healing and regeneratio in the skin, have become the leading role in increasing new treatment technologies of these repair and healing options.
Fibroblasts, which attract great attention in the field of aesthetics, secrete molecules that strengthen the elasticity and structural strength of the skin as the main cells of the connective tissue; They play an active role in maintaining the moisture content of the skin tissue. These molecules are the main source of development on anti-aging products and treatments.
It is natural that human skin goes through the process of biological change after 25 to 30 years of age. Collagen, hyaluronic acid and elastin, which are important building blocks of intercellular tissues, begin to decrease. In this case, as the age progresses, the skin begins to thin, and the fullness and elasticity of the skin decreases. Conclusion is the start of wrinkles on the skin and their deepening over time. Every 8-10 years, the rate of fibroblasts in the skin continues to decrease by 10-15%.
Collagen produced by fibroblast cells is an important criteria of intercellular tissue strength. As aging continues, fibroblast cells in the connective tissue decrease. As a result, the release properties of auxiliary substances are also reduced. Of course, there are ways to prevent this not-so-likeable trend. When the elasticity and regeneration power of the tissues decrease, regenerative techniques come into play. The fibroblast cells in the person's skin can be injected into the person himself to achieve this purpose. The process of freezing fibroblasts taken at a young age is the most reliable way.
Fibroblasts preserved by this method can be stored for many years without the slightest loss of vitality and can be used repeatedly. Fibroblasts used by thawing from frozen state, when re-injected into the skin, produce all the components and molecules needed by the intercellular tissue and give them to the environment they need. As a result of this process, the elasticity of the skin increases and the structural resistance increases. The skin looks healthier and the aging process is slowed down.
This type of "anti-aging" process is considered to be the most natural method since one's own biological reserve is used..
May the beauty never diminish in your life...